Presentation: Luteal Phase Support

Kaylen M. Silverberg, MD  
Founding Partner & Medical Director
Texas Fertility Centers & Austin IVF
Austin and San Antonio, TX 


Learning Objectives

After viewing this presentation, the participant should be able to:
  • Explain the advantages of stimulated/artificial FET cycles, even though both natural and stimulated cycles produce excellent pregnancy rates
  • Identify the modes of delivery for endometrial stimulation with estradiol that can be readily accomplished
  • Explore why luteal progesterone supplementation remains controversial in natural cycles
  • Although PIO was once the gold standard, explain why vaginal progesterone is considered be equally efficacious
  • Assess the role of vaginal gel in contributing toward excellent pregnancy rates
  • Discuss the role of vaginal tablets in combination with oral prometrium or PIO in achieving optimal results
  • Describe alternative combination regimens that may be superior to PIO alone and/or vaginal P4 alone


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Target Audience

This activity is intended for the education of nurses and nurse practitioners specializing in reproductive medicine and assisted reproductive technologies.

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Requirements for Successful Completion

To successfully complete this activity for CE credit, the participant will:
1. Take the pretest
2. Review the content in the presentation
3. Complete the posttest with a score of at least 3 correct answers
4. Fill out a brief evaluation


Upon completion of the requirements 1 – 4, a CE certificate will be available for download.


Release & Expiration Dates
July 2021 — February 2022


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Disclosure Information and Off-Label Uses
It is the policy of Letters & Sciences to ensure balance, independence, objectivity, and scientific rigor in all their sponsored educational activities. All faculty members participating in this activity are expected to disclose to the learners any real or perceived conflicts of interest related to the content of their presentations.

It is not assumed that any financial interests or affiliations will have an adverse impact on the faculty presentations. They simply are noted here to fully inform participants.


Elizabeth S. Ginsburg, MD
  • Has received royalties from UptoDate, Biomed Central
  • Has received consulting fees from Teledoc, Sanders and Parks
  • Has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in her presentation

William H. Kutteh, MD, PhD, HCLD
  • Has received research grant support from Ferring Pharmaceuticals and Natera
  • Has served as consultant for Natera
  • Has served as a speaker for AbbVie
  • Will not be discussing or referring to unlabeled/unapproved uses of drugs, devices, products, protocols, or therapeutic strategies

Craig S. Niederberger, MD, FACS
  • Has no relationships to disclose
  • Will be discussing off-label uses of rFSH, hMG, clomiphene, tamoxifen, anastrozole, and testolactone

Kaylen M. Silverberg, MD
  • Has served as a consultant to AbbVie, Baxter, and EMD Serono
  • Will be discussing or referring to unlabeled/unapproved uses of oral progesterone

Hugh S. Taylor, MD
  • Has received grant/research support from Abbvie
  • Has Founders Options: DOTLab
  • Has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation

Executive Committee, CNE Committee, Planning Committee, Curriculum Committee Members
etters & Sciences, the content managers/members of the planning, executive and curriculum committees, report no relationships with commercial interests.

External Review
In accordance with the policies of Letters & Sciences, and in compliance with the standards of ANCC and ACCME to identify and resolve any potential conflicts of interest, to assure fair balance, independence and objectivity, and to instill scientific rigor in all accredited activities, all presentations with any potential for conflicts of interest, have been reviewed by external reviewers. The external reviewers, who have no potential conflicts of interest, have determined that no bias exists in these presentations. The external reviewers are:

Shannon L. DeVita, MSN, RN, CNL, DNP
Nurse Practionier
San Diego, California

Michele Nichols, PharmD
Pharmacy Consultant
Private Practice
Raritan, New Jersey
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Accreditation Statements

Continuing Nursing Education with Distinction & Credit Designation
Letters & Sciences is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Each activity has been designated for 0.5 contact hours.

Nonendorsement of Products
The learner is advised that the educational content contained herein was developed by and reflects the opinions of the presenters and faculty, and does not necessarily reflect the opinions or recommendations of the educational provider or the grantors. Accredited status does not imply endorsement by Letters & Sciences or the American Nurses Credentialing Center’s Commission on Accreditation of any commercial product discussed/displayed in conjunction with the educational activities.

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Commercial Support

This activity is supported by educational grants from EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, and Ferring Pharmaceuticals, Inc.


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Each CNE activity on this website is eligible for individual credit.